Adamowicz EM, Harcombe WR (2020) Weakest-link dynamics predict apparent antibiotic interactions in a microbial cross-feeding community. Antimicrobial Agents and Chemotherapy 64 e00465-20
Fazzino L, Anisman J, Chacón JM, Harcombe WR (2020) Phage cocktail strategies for the suppression of a pathogen in a cross-feeding co-culture. Microbial Biotechnology 13 1997-2007.
Adamowicz EM, Muza M, Chacón JM, Harcombe WR (2020) Cross-feeding modulates the rate and mechanism of antibiotic resistance evolution in a model microbial community of Escherichia coli and Salmonella enterica. PLoS Pathogens. 16 e1008700.
Chacón JM, Shaw AK, Harcombe WR (2020) Increasing growth rate slows adaptation when genotypes compete for diffusing resources. PLoS Computational Biology. 16 e10007585.
Flynn JM, Cameron LC, Wiggen TD, Dunitz JM, Harcombe WR, Hunter RC (2020) Disruption of cross-feeding inhibits pathogen growth in the sputa of patients with cystic fibrosis. mSphere. 5 e00343.
Fazzino L, Anisman J, Chacón JM, Heineman RH, Harcombe WR (2020) Lytic bacteriophage have diverse indirect effects in a synthetic cross-feeding community. ISME 14 123-134.
Hammarlund SP, Harcombe WR. (2019) Refining the stress gradient hypothesis in a microbial community. PNAS. 201910420
Chacón JM, Harcombe WR. (2019) The power of metabolism for predicting microbial community dynamics. mSystems 4: e00146-19
Hammarlund SP, Chacón JM, Harcombe WR. (2019) A shared limiting resource leads to competitive exclusion in a cross-feeding system. Environmental Microbiology. 21:759-71.
Harcombe WR, Chacón JM, Adamowicz EM, Chubiz LM, Marx CJ. (2018) Evolution of bidirectional costly mutualism from byproduct consumption. PNAS. 115: 12000-12004 link
Adamowicz EM, Flynn J, Hunter RC, Harcombe WR (2018) Cross-feeding modulates antibiotic tolerance in bacterial communities. ISME. 12:2723-2735 link
Chacón JM, Moebius W, Harcombe WR (2018) The spatial and metabolic basis of colony size variation. ISME 12:669-680. link
Estrela S, Libby E, Van Cleve J, Debarre F, Deforet M, Harcombe WR, Pena J, Brown SP, Hochberg ME. (2018) Environmentally mediated social dilemmas. Trends in Ecology and Evolution. link
Carlson RP, Beck AE, Phalak P, Fields MW, Gedeon T, Hanley L, Harcombe WR, Henson MA, Heys JJ. (2018) Competitive resource allocation to metabolic pathways contributes to overflow metabolisms and emergent properties in cross feeding consortia. Biochemical Society Transactions. link
Maselko M, Heinsh SC, Chacón JM, Harcombe WR, Smanski MJ (2017) Engineering species-like barriers to sexual reproduction. Nature Communications. 8: 883 link
Douglas SM, Chubiz LM, Harcombe WR, Marx CJ (2017) Identification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation. PLoS One 12(5), e0174345
Harcombe WR, Betts A, Shaprio JW, Marx CJ. (2016) Adding biotic complexity alters the metabolic benefits of mutualism. Evolution. 70:1871-1881. pdf
Chacón JM, Harcombe WR. (2016) Antimicrobials: Constraints on microbial warfare. Nature Microbiology 1:16225. pdf
Douglas SM, Chubiz LM, Harcombe WR, Ytreberg FM, Marx CJ. (2016) Parallel mutations Result in a wide range of cooperation and community consequences in a two-species consortium. PLoS One 11:e0161837. pdf
Chubiz LM, Granger BR, Segre D, Harcombe WR. (2015) Species interactions differ in their genetic robustness. Frontiers in Microbiology 6:271. pdf
Harcombe, W.R.*, Riehl, W*., Dukovski, I., Granger, B.R. Betts, A., Lang, A.H. Bonilla, G., Kar, A., Leiby, N., Mehta, P., Marx, C.J., Segre, D. (2014) Predicting the spatio-temporal dynamics of microbial community metabolism. Cell Reports 7(4):1104-1115. pdf
Plucain, J. Hindre, T., Le Gac M., Tenaillon, O., Cruvioller, S., Medigue, C., Leiby. N., Harcombe, W.R., Marx, C.J., Lenski, R., Schnedier, D. (2014) Epistasis and allele specificity in the emergence of a stable polymorphism in Escherichia coli. Science 343(6177):1366-1369. pdf
Chubiz, L. Douglas, S. Harcombe, W.R. (2014) Combining engineering and evolution to create metabolic mutualisms between species. Methods in Molecular Biology 1151:39-47.